Landes Highlights

the intestinal mucosal immune system is challenged with bacteria, viruses, and parasites, in addition to food and environmental antigens, that require dynamic immune responsiveness for homeostasis. a recent review by dr Kenneth Kudsk and coworkers highlights the recognized roles of JaK-stat signaling in the intestinal mucosal immune system in the regulation of both, adaptive and innate mucosal immune function, as well as epithelial repair and regeneration. adaptive immunity includes lymphocyte mediated secretion of specific JAK-STAT and intestinal mucosal immunology